Meet Jamie Shirey, FNP-BC: Founder of Midlifesy & Expert in Hormone and Wellness Care

DEDICATED TO HELPING MIDLIFE WOMEN AND MEN RESTORE BALANCE, ENERGY, AND CONFIDENCE THROUGH PERSONALIZED CARE THAT GOES BEYOND TRADITIONAL HEALTHCARE

Hi, I’m Jamie Shirey

When I hit menopause, I was juggling a demanding career, raising five teenagers, and battling unexplained weight gain, exhaustion, and brain fog. Like many women, I turned to my doctors for help. The answers? “Eat less and move more.” Or worse: “This is just aging.”

But as a Nurse Practitioner with over 25 years in healthcare, I knew women deserved better—answers, not dismissals. Solutions, not symptom band‑aids.

📍Serving midlife women across Pennsylvania (in person & via telehealth)

I know how frustrating midlife can feel—because I’ve lived it too.

“You’re not broken. You’re just ready to SHIFT.”

Founder, Midlifesy • Nurse Practitioner (25+ yrs)

Why I Started Midlifesy

I founded Midlifesy to change the way women experience midlife and menopause. We’re not bound by the limitations of insurance companies or one‑size‑fits‑all protocols. Instead, we look at your whole picture—hormones, metabolism, sleep, stress, and lifestyle.

Using advanced biomarker testing, personalized hormone therapy, and targeted lifestyle strategies, we uncover and address the root causes of fatigue, weight gain, mood swings, and brain fog—so you can feel like yourself again.

The SHIFT Method™

A five‑phase framework designed to restore balance and unlock your best midlife.

Sleep & Stress

Reset your rhythm, lower cortisol, and repair rest.

Hormone Harmony

Identify imbalances with labs and restore what’s missing.

Inflammation & Insulin

Lower inflammation and improve blood sugar for steady energy.

Fitness & Function

Rebuild strength, stamina, and daily resilience.

Transformation & Tracking

Sustain progress with monitoring and long‑term support.

What This Means For You

My mission is simple: to help midlife women go from exhausted, imbalanced, and dismissed… to energized, hormonally balanced, and confident in their health again. Because midlife isn’t a crisis—it’s your catalyst.

  • Personalized biomarker‑driven plan

  • Thoughtful use of HRT when appropriate

  • Practical nutrition & lifestyle strategies

  • Ongoing support and follow‑up

You’re Not Broken—You’re Ready to SHIFT

If you’ve been told your symptoms are “just aging,” you’re in the right place. The next step is simple—and it’s designed to give you clarity.


A Little More About Me

Beyond the clinic—what lights me up.

Family First

Five grown kids, two granddaughters, and lots of joyful chaos.

Adventure Buddies

Traveling with my husband whenever we can steal a long weekend.

Meet Mia

Our Papillon pup—and my agility training partner.

Creative Outlets

Photography, crafts, and the occasional DIY furniture project.

woman wrapped in a white towel with a white towel on her head looking out a window

Hormone Harmony  Reset Roadmap

Our Hormone Harmony Reset Roadmap integrates tailored hormone therapies, customized supplements, and expert support to address midlife hormonal imbalances. This comprehensive package is designed to restore balance, alleviate symptoms, and help you feel vibrant, confident, and in control of your well-being.

rose colored dishes with makeup powder in them

Metabolic Reset Roadmap

The Midlifesy Metabolic Reset Roadmap combines cutting-edge Semaglutide therapy, targeted supplements, and personalized coaching to optimize your metabolism and support sustainable weight loss. This holistic program empowers you to reclaim your energy, achieve lasting results, and embrace a healthier, balanced life.

Confident midlife woman in a textured beige dress with puffy sleeves, representing empowered aging and hormone-balanced vitality with Midlifesy

All Natural Skin Rejuvenation

Our Microneedling with PRF Rejuvenation treatment is a natural, cutting-edge solution designed to revitalize your skin by harnessing your body’s own healing properties. This innovative approach combines the power of microneedling with Platelet-Rich Fibrin (PRF) to stimulate collagen production, improve skin texture, and enhance overall radiance. Ideal for addressing fine lines, acne scars, uneven tone, and signs of aging, this treatment promotes vibrant, healthy-looking skin without synthetic chemicals or lengthy downtime.

aesthetic photo of water, matcha and supplements in a gold dish

Men’s Peak Performance Roadmap

A complete program featuring testosterone replacement therapy, customized supplementation, and strategic lifestyle planning. Unlock your potential and achieve peak performance with a program tailored to help men restore energy, strength, and vitality. This holistic approach is designed to optimize your physical and mental performance for long-term results. Our all-inclusive package includes:

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“I Cannot Recommend this Practice Enough”

“Jamie was thorough & took the time to explain everything to me! I cannot recommend this practice enough." Meredith H.